Niacin Inhibits Vascular Inflammation via Downregulating Nuclear Transcription Factor-κB Signaling Pathway

Figure 2

Niacin and simvastatin suppressed the expression of nuclear protein NF-κB p65 in the arterial wall of guinea pigs fed high fat diet. The protein expression was analyzed by western blot and normalized to histone H3 level. (a) shows the representative image by western blot. (b) shows the IOD ratio of NF-κB p65 to Histone H3. Data are presented as mean ± SD of at least three independent experiments. ^##𝑃<0.01 versus CD group; ^∗∗𝑃<0.01 versus HFD group.

(a)

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