Niacin Inhibits Vascular Inflammation via Downregulating Nuclear Transcription Factor-κB Signaling Pathway

Figure 6

Niacin and simvastatin significantly lessened lipid deposition in the arterial wall of guinea pigs fed high fat diet. Lipid deposition in the aorta wall was analyzed by oil red O staining after treatment for 8 weeks. The quantification of stained lipids was determined by calculating the percentage of the positive area to the total cross-sectional vessel wall area by Image-Pro Plus software. Data are presented as mean ± SD (𝑛=8). ^##𝑃<0.01 versus CD group; ^∗∗𝑃<0.01 versus HFD group.

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