Mediators of Inflammation / 2014 / Article / Tab 2

Research Article

Relationship between Early Inflammatory Response and Clinical Evolution of the Severe Multiorgan Failure in Mechanical Circulatory Support-Treated Patients

Table 2

Preimplant inflammatory characteristics.

All casesmax tSOFA score < 11max tSOFA score ≥ 11
( )(Group A = 32)Outcome + (group B = 8)Outcome − (group C = 13)

TNF- , pg/mL9.3 (5.2–12.1)6.9 (5.0–10.4)10.3 (2.6–16.3)9.7 (9.4–14.0)0.081
IL-6, pg/mL9.8 (3.6–27.4)6.8 (3.0–24.1)17.8 (6.1–118.7)25.6 (9.6–63.4)0.067
IL-8, pg/mL7.6 (5.2–13.6)7.7 (5.5–11.3)5.1 (3.7–14.4)13.1 (5.3–24.2)0.294
C-reactive protein, mg/dL1.5 (0.5–3.9)1.2 (0.3–3.1)2.2 (0.8–13.1)2.2 (1.1–8.4)0.108
IL-10, pg/mL1.8 (0–7.5)1.8 (0–8.0)1.7 (0–6.2)2.2 (0–14.4)0.824
IL-1ra, pg/mL518 (311–1276)491 (295–840)785 (268–1955)828 (468–1898)0.137
sICAM-1, pg/mL300 (224–433)291 (226–397)332 (220–676)323 (210–528)0.739
sP-selectin/PLT, pg/106288 (164–505)221 (173–476)410 (217–622)337 (122–537)0.742
Neo/Cr ratio, mol/mol290 (199–563)279 (181–457)317 (128–549)337 (240–698)0.422

Data are expressed as median and interquartile range (25th–75th).
IL: interleukin; Neo/Cr: neopterin levels normalized by urine creatinine levels; sICAM-1: soluble form of intercellular adhesion molecule type 1; sP-selectin/PLT: soluble platelet selectin normalized by platelet count; TNF: tumor necrosis factor; +: positive; −: negative.