Macrophage Trafficking as Key Mediator of Adenine-Induced Kidney Injury
Figure 2
DHA crystals and macrophage localization after excessive adenine intake in WT, clodronate treated, CCR5, and CCL3 KO animals. (a) HE staining of the groups mentioned before showing the DHA crystals deposition in renal tissue, indicated by red arrows. In panel (b), IHC for CD11b is represented, showing macrophage infiltration in the different groups.
