Anabolic Properties of High Mobility Group Box Protein-1 in Human Periodontal Ligament Cells In Vitro

Figure 5

HMGB1 upregulates osteocalcin protein expression. In addition later stages of maturation were also affected by HMGB1. Enhanced osteocalcin protein expression was demonstrated, both in immunofluorescent stainings and by osteocalcin ELISA. Data represent the mean ± SD for six independent cultures. , experimental group versus untreated control.

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