Adiponectin and Atherosclerosis in Rheumatoid Arthritis

Table 1

Total and high molecular weight adiponectin in all 210 RA patients and subgroups.

Groups	Number	Total adiponectin		HMW adiponectin
		(ng/mL)		(ng/mL)
		Median (IQR)	𝑃	Median (IQR)	𝑃
All	210	7.41 (4.89–11.97)	—	3.26 (1.27–5.74)	—
Population
Black	119	7.41 (5.62–11.56)		2.65 (1.55–5.53)
White	91	7.25 (5.31–12.83)	0.9	3.82 (2.10–6.00)	0.9
Age >55 years
Yes	122	7.45 (5.20–13.58)		3.58 (1.86–6.18)
No	88	6.84 (4.67–10.13)	0.2	2.67 (1.38–4.76)	0.1
≥2 major risk factors
Yes	146	7.17 (4.62–11.39)		2.99 (1.53–5.40)
No	55	8.48 (5.90–13.28)	0.1	3.78 (2.07–6.32)	1.0
Missing	9
Obesity
Yes	64	6.91 (4.32–9.76)		2.56 (1.26–4.96)
No	140	7.58 (5.28–13.23)	0.7	3.47 (2.00–6.09)	0.9
Missing	6
MetS waist
Yes	100	6.47 (4.32–10.01)		2.66 (1.42–4.76)
No	107	8.38 (5.32–13.63)	0.02	3.57 (2.03–6.48)	0.3
Missing	3
RA duration >10 years
Yes	109	7.41 (4.99–12.96)		3.44 (1.74–6.13)
No	100	7.32 (4.32–11.29)	0.5	2.80 (1.53–4.94)	0.9
Missing	1
CDAI >10
Yes	93	7.51 (4.65–11.94)		3.33 (1.57–5.69)
No	116	7.35 (5.04–12.83)	0.4	3.26 (1.98–5.87)	0.8
Missing	1
ESR >12 mm/hr
Yes	116	7.38 (4.50–11.29)		3.29 (1.69–5.60)
No	87	7.87 (5.31–12.92)	0.4	3.26 (1.71–5.90)	0.8
Missing	7
Deformed joints
Yes	162	7.97 (5.19–13.58)		3.51 (1.81–6.00)
No	47	5.36 (3.55–8.56)	0.0003	2.34 (1.38–4.14)	0.02
Missing	1
RF positive
Yes	161	7.41 (4.90–11.23)		3.27 (1.78–5.58)
No	48	7.51 (3.95–15.03)	0.7	2.74 (1.29–6.49)	0.6
Missing	1

Associations were identified in age, sex, race, glomerular filtration rate, cardiovascular drug use, and waist circumference adjusted models. Significant associations are shown in bold. RA: rheumatoid arthritis; HMW: high molecular weight; IQR: interquartile range; MetS: metabolic syndrome; CDAI: Clinical Disease Activity Index; ESR: erythrocyte sedimentation rate; RF: rheumatoid factor.