Obesity and Low-Grade Inflammation Increase Plasma Follistatin-Like 3 in Humans
Table 3
Associations between plasma follistatin-like 3 and biochemical and demographic markers in obese and nonobese subjects.
Nonobese (BMI < 30) ()
Obese (BMI > 30) ()
Spearman’s
Spearman’s
Age (years)
0.334***
0.350***
Weight (kg)
−0.091
−0.045
Height (m)
−0.164
−0.276**
Hip (cm)
−0.002
0.376***
Waist (cm)
0.079
0.207*
BMI (kg/m2)
0.128
0.228*
Systolic BP (mmHg)
−0.106
0.046
Diastolic BP (mmHg)
−0.108
0.087
VO2max/(mL/min/kg)
−0.149
−0.285**
Whole body fat (kg)
0.312**
0.466***
Trunk fat mass (kg)
0.254*
0.384**
Whole body fat-free mass (kg)
−0.263*
−0.311**
Insulin fasting (pM)
0.292**
0.195*
Glucose fasting (mM)
−0.131
0.138
c-peptide (nM)
0.282**
0.303**
HOMA B
0.342***
0.064
HOMA S
−0.217*
−0.224*
TNF-alpha (pg/mL)
0.334***
0.273**
IL-6 (pg/mL)
0.409***
0.265**
Leptin (pg/mL)
0.386***
0.551***
Adiponectin (ug/mL)
0.168
0.191
Spearman’s correlation coefficient is given for each variable. The nonobese group included 97 subjects. The obese group consisted of 103 subjects except for hip (102), waist (102), VO2max (102), and whole body fat (101). HOMA S: homeostasis model assessment of insulin sensitivity. HOMA B: homeostasis model assessment of beta cell function. BMI: body mass index indicates a significant correlation between plasma fstl3 and the given variable. , , and .
