Placental Origin of Prostaglandin F2α in the Domestic Cat
Figure 1
PGFS (AKR1C3) protein localization in the uteroplacental unit. Immunohistochemical (IHC) localization of PGFS in the week 2 of pregnant uterus (a) and placenta at week 3 (b), week 6 (c), and week 9 of gestation ((d), (e)). (a) In the feline uterus some weak PGFS signals are localized in the glandular epithelium (open arrowheads); ((b), (c)) in the placental labyrinth, PGFS expression is localized in the fetal trophoblast cells (solid arrowheads). ((d), (e)) In the fully developed placenta, towards the end of pregnancy, signals are weaker in trophoblast cells and are mostly localized in maternal decidual cells (open arrowheads). (f) Isotype control.
