Clinical Value of Plasma Soluble Urokinase-Type Plasminogen Activator Receptor Levels in Term Neonates with Infection or Sepsis: A Prospective Study
Table 2
Demographic, clinical characteristics, and laboratory findings in infants with bacterial and viral infections on admission to the Unit and in controls.
Bacterial infections (N = 19)
Viral infections (N = 28)
Controls (N = 18)
Gestational age (weeks)
38.5 ± 1.0
38.9 ± 1.0
38.6 ± 1.0
Birth weight (g)
3033 ± 285
3203 ± 379
3216 ± 406
Postnatal age (days)
17.4 ± 5.9
18.0 ± 6.6
17.0 ± 6.0
Males
13
16
11
Fever duration (hours)
<8
12
19
8–24
6
6
N/A
>24
1
3
Max temperature (°C)
38.4 ± 0.56* (37.8–40.0)
38.2 ± 0.45* (37.8–39.5)
36.7 ± 0.08 (36.6–36.9)
Fever recession following admission (hours)
<36
14
21
36–72
5
4
N/A
>72
0
3
WBC (/mm3)
(1970–25340)
10141 ± 4000 (3670–17560)
9227 ± 2630 (5260–14580)
ANC (/mm3)
(768–15176)
3816 ± 2533 (770–11388)
2867 ± 1257 (1052–5233)
Immature neutrophils (/mm3)
48.7 ± 172.0 (0–746)
0
0
Platelet count (/mm3)
505300 ± 200800 (37000–920000)
429000 ± 141000 (187000–806000)
448000 ± 171000 (250000–714000)
Urea (mg/dL)
(11.0–71.0)
14.1 ± 6.4 (4.0–30.0)
12.8 ± 7.3 (5.0–35.0)
Creatinine (mg/dL)
0.34 ± 0.14 (0.10–0.65)
0.29 ± 0.08 (0.18–0.48)
0.31 ± 0.18 (0.10–0.73)
SGOT (IU/L)
34.1 ± 25.7 (6.0–129.0)
37.2 ± 25.4 (20.0–148.0)
42.8 ± 12.9 (22.0–60.0)
SGPT (IU/L)
26.1 ± 8.8 (7.0–45.0)
26.6 ± 18.0 (9.0–104.0)
25.8 ± 14.2 (12.0–59.0)
γ-GT (IU/L)
87.6 ± 36.0 (30.0–163.0)
90.0 ± 43.0 (22.0–225.0)
110.8 ± 46.2 (41.0–207.0)
CRP (mg/L)
(0.2–273.0)
10.8 ± 28.9 (0.2–137.0)
0.56 ± 0.57 (0.2–1.8)
suPAR (ng/mL)
5.38 ± 1.92* (3.52–9.24)
4.73 ± 1.11‡ (2.69–7.83)
3.61 ± 0.74 (2.38–4.79)
N/A: not applicable. Quantitative variables are expressed as mean ± S.D (range). P ≤ 0.001, ‡P ≤ 0.05 compared with controls; P ≤ 0.001 compared with the viral infection group.
