The Influence of Autologous Bone Marrow Stem Cell Transplantation on Matrix Metalloproteinases in Patients Treated for Acute ST-Elevation Myocardial Infarction

Table 2

Circulating levels of MMP-9, TIMP-1, and EMMPRIN at baseline and follow-up in the randomized groups. Median values (25th and 75th percentiles) are given.

	Baseline (Day-1)		Day 1		Day 3		2-3 weeks		3 months
	mBMC	Control	mBMC	Control	mBMC	Control	mBMC	Control	mBMC	Control
MMP-9; (ng/mL)	205; (79, 419)	235; (83, 502)	286; (98, 432)	276; (103, 518)	287; (115, 426)	273; (116, 499)	281^*†; (141, 574)	302; (106, 419)	270^†; (153, 410)	210; (110, 398)
TIMP-1; (ng/mL)	211; (158, 326)	228; (151, 327)	234; (157, 326)	253; (158, 354)	222; (173, 322)	253; (182, 333)	216; (171, 336)	213; (172, 306)	204; (164, 282)	220; (182, 273)
EMMPRIN; (pg/mL)	4324; (3663, 4878)	4329; (3752, 4994)	4317; (3739, 4966)	4357; (3976, 4952)	4339; (3667, 4837)	4367; (3768, 4853)	3754 *; (3249, 4436)	3857 *; (3440, 4476)	3654 *; (3312, 4099)	3775 *; (3364, 4245)

No differences between the groups were observed at any time points.
*Refers to value < 0.05 for intragroup changes from baseline to later time points.
^†Refers to value ≤ 0.05 for differences in changes from baseline between the groups.