Mediators of Inflammation / 2014 / Article / Tab 2

Research Article

The Influence of Autologous Bone Marrow Stem Cell Transplantation on Matrix Metalloproteinases in Patients Treated for Acute ST-Elevation Myocardial Infarction

Table 2

Circulating levels of MMP-9, TIMP-1, and EMMPRIN at baseline and follow-up in the randomized groups. Median values (25th and 75th percentiles) are given.

Baseline (Day-1)Day 1Day 32-3 weeks3 months
mBMC Control mBMC Control mBMC Control mBMC Control mBMC Control

MMP-9
(ng/mL)
205
(79, 419)
235
(83, 502)
286
(98, 432)
276
(103, 518)
287
(115, 426)
273
(116, 499)
281*†
(141, 574)
302
(106, 419)
270
(153, 410)
210
(110, 398)

TIMP-1
(ng/mL)
211
(158, 326)
228
(151, 327)
234
(157, 326)
253
(158, 354)
222
(173, 322)
253
(182, 333)
216
(171, 336)
213
(172, 306)
204
(164, 282)
220
(182, 273)

EMMPRIN
(pg/mL)
4324
(3663, 4878)
4329
(3752, 4994)
4317
(3739, 4966)
4357
(3976, 4952)
4339
(3667, 4837)
4367
(3768, 4853)
3754 * 
(3249, 4436)
3857 * 
(3440, 4476)
3654 * 
(3312, 4099)
3775 * 
(3364, 4245)

No differences between the groups were observed at any time points.
*Refers to value < 0.05 for intragroup changes from baseline to later time points.
Refers to value ≤ 0.05 for differences in changes from baseline between the groups.