Hesperidin Inhibits Inflammatory Response Induced by Aeromonas hydrophila Infection and Alters CD4+/CD8+ T Cell Ratio
Figure 2
In vivo effect of hesperidin inoculation on phagocytic activities in blood (NBT index) (a) and intestinal reactive oxygen species (ROS) production (b). Mice were infected, each with 2 × 108 CFU of Aeromonas hydrophila per week for four consecutive weeks (B-infected group), and treated simultaneously with hesperidin at a dose of 250 mg/kg/week for four consecutive weeks (HES-treated group). At the end of week 4 following exposure and treatment, mice were sacrificed and weighted, the liver, spleen, and intestine were weighted, phagocytic activity was estimated in fresh blood, and intestinal ROS production was evaluated in intestinal homogenate. Values not sharing common superscripts denote significant differences.
