Low Intraprostatic DHT Promotes the Infiltration of CD8+ T Cells in BPH Tissues via Modulation of CCL5 Secretion

Figure 1

The T-cell population infiltrating prostate tissue with/without finasteride treatment. (a) CD8 was stained from no medication group and finasteride group; scale bar: 100 μm and 20 μm. Negative controls were showed in the bottom left corner, respectively. Data presented as the percentage of CD8+ T-cell number in all of nuclear cell number (mean ± SEM); ^∗𝑃=0.013 (𝑡-test). (b) Immunohistochemistry staining for CD4+ T infiltration. Magnification and negative control are the same as mentioned before. (c) Flow cytometry assay. Data presented as the rate of CD8+ or CD4+ T cells in total T cell (mean ± SEM). ^∗𝑃=0.003 in the right column, (𝑡-test).

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