Low Intraprostatic DHT Promotes the Infiltration of CD8+ T Cells in BPH Tissues via Modulation of CCL5 Secretion
The T-cell population infiltrating prostate tissue with/without finasteride treatment. (a) CD8 was stained from no medication group and finasteride group; scale bar: 100 μm and 20 μm. Negative controls were showed in the bottom left corner, respectively. Data presented as the percentage of CD8+ T-cell number in all of nuclear cell number (mean ± SEM); (-test). (b) Immunohistochemistry staining for CD4+ T infiltration. Magnification and negative control are the same as mentioned before. (c) Flow cytometry assay. Data presented as the rate of CD8+ or CD4+ T cells in total T cell (mean ± SEM). in the right column, (-test).