Association of Immune and Metabolic Receptors C5aR and C5L2 with Adiposity in Women

Figure 1

Circulating ASP and ASP to C5L2 ratio are associated with adiposity. Subcutaneous (a) and omental (b) C5L2 mRNA expression for normal/overweight (open bar), obese group I (dotted bar), obese group II (striped bar), and obese group III (checkered bars), (c) plasma ASP for normal/overweight (open bar), obese group I (dotted bar), obese group II (striped bar), and obese group III (checkered bars), and (d) ASP/C5L2 ratio in subcutaneous adipose tissue (open bars) and omental adipose tissue (checkered bars). Results are expressed as means ± SEM; 𝑛= 33–36 per group. Statistical differences were determined by Student’s 𝑡-test and one-way ANOVA, for normal/overweight versus obese groups and for SC versus OM groups, where *𝑃<0.05 and **𝑃<0.001.

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