Dendritic Cells from Aged Subjects Display Enhanced Inflammatory Responses to Chlamydophila pneumoniae
Conventional Myeloid DCs (cDCs) from the blood of aged subjects also display enhanced inflammatory responses to CPn. Graphs depict the levels of cytokine and chemokines secreted by CPn-stimulated cDCs purified directly from the blood of aged and young subjects. (a) TNF-; (b) CXCL-10; (c) IL-6; (d) IL-10; (e) IFN-; Each dot corresponds to a separate subject. Data is of 8 aged and 8 young subjects. value depicted is comparison of CPn-stimulated DCs from aged with their young counterparts.