Importins and Exportins Regulating Allergic Immune Responses

Figure 2

Schematic diagram showing the involvement of transcriptional factors in response to key mediators of allergic inflammation: binding of Th2 cytokines to their specific receptors and the activation of the downstream JAK/STAT pathways specific to each cytokine are shown. JAK: Janus activated kinase; NPC: nuclear pore complex; STAT: signal transducer and activator of transcription; TyK2: tyrosine kinase 2.