Dynamics of Acute Local Inflammatory Response after Autologous Transplantation of Muscle-Derived Cells into the Skeletal Muscle

Figure 2

The analysis of cytokines gene expression in the muscle tissue determined by real-time PCR. The graphs represent relative gene expression of Il-1α, Il-1β, Il-6, Tgf-β,and Tnf-α in animals’ muscles from different groups: untreated control (CTRL), after vehicle injection (VEH), and after MDCs transplantation (MDC) 1, 3, and 7 days after surgery. Results were analyzed in pairs (untreated control versus VEH and VEH versus MDC) using nonparametric U Mann-Whitney test. indicates statistically significant difference between MDC and VEH groups and ^#indicates statistically significant difference between VEH and CTRL groups in certain time points.