Puerarin Alleviates Neuropathic Pain by Inhibiting Neuroinflammation in Spinal Cord
Figure 4
The effects of puerarin on diabetes-induced microglia and astroglia activation in ipsilateral spinal dorsal horn of rats. (a) and (b) Representative images of ipsilateral spinal dorsal microglia (a) and astroglia (b) activation in control rats, diabetic rats receiving vehicle, 20 and 100 nM puerarin on the 27th day after streptozotocin injection. Scale bar: 100 μm. (c) Quantification of microglia and astroglia activation in the spinal cord on the 27th day after streptozotocin injection. Data are presented as mean ± SEM. , diabetic rats versus control; , puerarin versus diabetes model (one-way ANOVA with post hoc LSD -test). Each group consisted of 6–10 rats.
