TRPV1 Antagonism by Capsazepine Modulates Innate Immune Response in Mice Infected with Plasmodium berghei ANKA
Figure 6
Effect of capsazepine on systemic lipid peroxidation and cytokine release. (a) Aldehyde; (b) TNFα and (c) IFNγ levels in plasma samples obtained from uninfected and Plasmodium berghei ANKA-infected mice (105 infected RBCs/animal; i.p.). Capsazepine (50 μg/animal, 2x day, for 6 days) was administered from 24 h after infection. Vehicle- (10% DMSO in saline) treated animals were used as controls. Data are expressed as mean ± SD, –8 per group. compared with vehicle-treated infected group.
