The Relationship between the Antitumor Effect of the IL-12 Gene Therapy and the Expression of Th1 Cytokines in an HPV16-Positive Murine Tumor Model
Figure 2
Long-term survival of animal after treatment. The antitumoral effect of IL-12 was evaluated in an HPV16-positive experimental tumor model. The groups of mice () were injected with plasmid pNGVL3-mIL-12 (asterisks), pcDNA3 plasmid (triangle), PBS (square), or no treatment as control (diamond). Mouse survival was evaluated each day after the treatment, increased survival of tumor-free mice treated with IL-12 compared with controls.
