Cardiac Fibroblasts Aggravate Viral Myocarditis: Cell Specific Coxsackievirus B3 Replication

Table 1

Hemodynamic function of B6 mice 7 days after CVB3 infection.

	B6-PBS treated	B6-CVB3 treated	value
Global function
Heart rate [bpm]	595 ± 13	549 ± 16	0.042
Cardiac output [μL/min]	26041 ± 2297	14838 ± 1669	0.004
Stroke volume [μL]	44 ± 4	27 ± 3	0.012
Stroke work [μL·mmHg]	3468 ± 440	1697 ± 244	0.007
Ejection fraction [%]	74 ± 3	67 ± 5	0.298
Systolic function
[mmHg]	84 ± 5	69 ± 3	0.029
dP/dtmax [mmHg/s]	9147 ± 893	6182 ± 663	0.042
[μL]	18 ± 3	14 ± 2	0.363
Diastolic function
[mmHg]	3.4 ± 0.5	2.3 ± 0.3	0.083
dP/dtmin [mmHg/s]	−5024 ± 451	−3565 ± 300	0.019
Tau [ms]	9.4 ± 0.2	11.8 ± 0.5	0.001
PHT [ms]	5.2 ± 0.2	7.0 ± 0.5	0.007
[μL]	60 ± 6	41 ± 3	0.019