Sitagliptin Prevents Inflammation and Apoptotic Cell Death in the Kidney of Type 2 Diabetic Animals

Table 1

Body weight and glycaemia in the control and diabetic ZDF rats, nontreated and treated with sitagliptin for 6 weeks.

Time	Initial time (20 wks)		Final time (26 wks)
Rat group	Control	Diabetic	Control	Diabetic
Parameters	(𝑛=8)	(𝑛=16)	Vehicle (𝑛=8)	Vehicle (𝑛=8)	Sita (𝑛=8)
BW (g)	407.8±7.3	394.6±6.5	438.2±4	370.4±11.8^∗∗	389.5±15.7
Glycaemia (mg/dL)	92.3±2.5	304.6±9.1^∗∗∗	88.8±2.9	425.4±10.3^∗∗∗	329.8±24.4^###

Values are means ± SEM of 𝑛 rats. ^∗∗𝑃<0.01 and ^∗∗∗𝑃<0.001 significantly different from age-matched control; ^###𝑃<0.001 significantly different from age-matched diabetic.