Research Article
IL-17 Genetic and Immunophenotypic Evaluation in Chronic Graft-versus-Host Disease
Table 2
Association between recipient and donor
IL17A (
) and IL-17F (
) genotypes and occurrence of systemic cGVHD.
| | Gene | IL17A (G197A)
genotype | (%) |
Systemic cGVHD | | IL17F (7488T/C)
genotype | (%) |
Systemic cGVHD | | |
A |
P |
A |
P |
| | Recipient | GG | 12 (35.3%)
|
9 |
3 | 0.03 | CC | 10 (23.8%) |
7 |
3 | NS | | AG | 13 (38.2%) |
11 |
2 | CT | 18 (42.9%) |
9 |
9 | | AA | 9 (26.5%) |
3 |
6 | TT | 14 (33.3%) |
10 |
4 |
| | Donor | GG | 11 (32.4%) |
7 |
4 | NS | CC | 9 (21.4%) |
7 |
2 | NS | | AG | 15 (44.1%) |
9 |
6 | CT | 19 (45.2%) |
12 |
7 | | AA | 8 (23.5%) |
7 |
1 | TT | 14 (33.4%) |
7 |
7 |
|
|
A: absent; P: present; NS: not significant; *Chi-square test.
|
