Increased Peripheral Proinflammatory T Helper Subsets Contribute to Cardiovascular Complications in Diabetic Patients
Table 5
Categorical analysis of odds ratios adjusted by age and sex.
Normal
Mildly elevated
Moderately elevated
Severely elevated
CD4+/Lym (%)
OR
0.615
0.824
2.371
CI
0.185–2.044
0.257–2.636
0.784–7.173
0.427
0.744
0.126
Th1/CD4+ (%)
OR
2.077
5.451
9.503
CI
0.523–8.241
1.456–20.413
2.500–36.116
0.299
0.012*
0.001**
Th17/CD4+ (%)
OR
0.649
3.000
4.584
CI
0.167–2.517
0.910–9.892
1.402–14.983
0.532
0.071
0.012*
Th22/CD4+ (%)
OR
0.713
2.667
7.125
CI
0.178–2.858
0.771–9.220
2.081–24.398
0.633
0.121
0.002**
CD4+ (#/L)
OR
0.533
1.174
1.196
CI
0.164–1.735
0.389–3.544
0.397–3.598
0.296
0.776
0.075
Th1 (#/L)
OR
0.942
2.543
5.717
CI
0.254–3.489
0.758–8.534
1.709–19.122
0.928
0.131
0.005**
Th17 (#/L)
OR
1.528
1.665
3.900
CI
0.454–5.145
0.513–5.400
1.217–12.495
0.493
0.396
0.022*
Th22 (#/L)
OR
3.113
68.002
112.9
CI
0.121–79.94
3.771–1233
6.192–2058
1.000
0.000**
0.000**
/Lym (%): percentage in total lymphocytes. #/L: absolute counts of corresponding Th cells per milliliter of peripheral blood. *: statistically significant at level of . **: statistically significant at level of .