Genetic Vaccination against Experimental Infection with Myotropic Parasite Strains of Trypanosoma cruzi
Table 2
Summary of the ECG records.
Days after challenge
Strain
Sinus arrhythmia mouse groups
values
G1
G2
G3
G1 × G2
G1 × G3
G2 × G3
90
Brazil
0/6
10/6
0/6
0.001
NS
0.012
120
Brazil
0/6
10/6
1/6
0.001
NS
0.044
150
Brazil
0/6
11/6
5/6
0.001
0.007
NS
180
Brazil
0/6
4/6
4/6
0.03
0.03
NS
90
Colombian
0/6
3/6
1/5
NS
NS
NS
120
Colombian
0/6
3/6
0/5
NS
NS
NS
150
Colombian
0/6
12/6
0/5
0.001
NS
0.013
180
Colombian
0/6
16/6
1/5
0.001
NS
0.022
Days after challenge
Strain
Atrioventricular block mouse groups
values
G1
G2
G3
G1 × G2
G1 × G3
G2 × G3
90
Brazil
0/6
36/6
46/6
0.001
0.001
NS
120
Brazil
0/6
19/6
22/6
0.001
0.001
NS
150
Brazil
0/6
5/6
6/6
0.007
0.001
NS
180
Brazil
0/6
5/6
3/6
0.007
NS
NS
90
Colombian
0/6
20/6
30/5
0.001
0.001
NS
120
Colombian
0/6
27/6
15/5
0.001
0.001
NS
150
Colombian
0/6
6/6
2/5
0.001
NS
NS
180
Colombian
0/6
10/6
10/5
0.001
0.001
NS
ECG record of mice challenged and treated as described in the legend of Figure 6(a). Values represent the number of episodes (sinus arrhythmia or atrioventricular block) recorded during one minute per total of mice analyzed and were compared by Fisher exact probability test.
