Epigallocatechin-3-gallate Ameliorates Seawater Aspiration-Induced Acute Lung Injury via Regulating Inflammatory Cytokines and Inhibiting JAK/STAT1 Pathway in Rats

Figure 11

Effect of seawater and EGCG pretreatment on the expression of JAK1, p-JAK1, JAK2 and p-JAK2 in the cell line NR8383. (a) mRNA expression of JAK1 in NR8383 cells. (b) mRNA expression of JAK2 in NR8383 cells. (c) Representative western blot for the JAK1, p-JAK1, JAK2, and p-JAK2 protein in different groups. (d)–(g) Summarized data of the JAK1 (d), p-JAK1 (e), JAK2 (f), and p-JAK2 (g) protein level in different groups. Data represent three independent experiments and are expressed as mean ± SEM; ^∗𝑃<0.05 versus control group; ^#𝑃<0.05 versus seawater group.

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