Epigallocatechin-3-gallate Ameliorates Seawater Aspiration-Induced Acute Lung Injury via Regulating Inflammatory Cytokines and Inhibiting JAK/STAT1 Pathway in Rats
Figure 7
Effect of EGCG pretreatment on pulmonary ultrastructure. (a) Control group: the normal alveolar epithelial cell type II and thin alveolar (AL) wall. (b) EGCG group: there was no obvious change in pulmonary ultrastructure compared with control group. (c) Seawater group: neutrophil (N) infiltration in the alveolar lumen and thickened alveolar wall were observed. Meanwhile, endoplasmic reticulum expanded and lamellar bodies (LB) emptying increased. (d) Seawater + EGCG group: the change of alveolar wall and the alveolar epithelial cell type II were alleviated compared with seawater group ((a) 5000×; (b) 4000×; (c) 5000×; (d) 8000×). NU: nucleus; ER: endoplasmic reticulum.
