Intraperitoneal Infusion of Mesenchymal Stem/Stromal Cells Prevents Experimental Autoimmune Uveitis in Mice

Figure 3

Assay for inflammation- and immune-related cytokines in LNs. Real-time RT-PCR analysis showed that the levels of IL-17A and IFN-𝛾 transcripts were increased in popliteal LNs on day 7 after EAU induction and significantly reduced by hMSCs (a). However, the levels of IL-10, TGF-β, and IL-6 were significantly increased by hMSCs (b, c). The levels of IL-1β, IL-12A, or IL-23 were not different between BSS- and hMSC-treated EAU mice (c, d). Data are presented in mean + SEM. 𝑛=5 in each group.

(a)

(b)

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(d)