Involvement of Different CD4⁺ T Cell Subsets Producing Granzyme B in the Immune Response to Leishmania major Antigens

Figure 3

Phenotyping of cells producing GrB and IFN-γ. Percentage of cells positive for GrB (a) or IFN-γ (b) analyzed ex-vivo in PBMCs of HZCL or HC. Results are shown as percentages of positive cells inside the CD3⁺ T cells gate. Results are expressed as the mean ± standard error of the mean of levels. Statistical analysis: ^∗𝑃<0.05, when comparing the stimulated cells to the unstimulated cells (Unst) and ^∗∗𝑃<0.05, when comparing HZCL to HC.

(a)

(b)