Immunomodulatory Effect of Red Onion (Allium cepa Linn) Scale Extract on Experimentally Induced Atypical Prostatic Hyperplasia in Wistar Rats
(a)-(b) Prostate of rats treated with RO scale extract in a dose of 75 mg/kg showing. (a) Irregularly dilated acini filled with secretions. Arrow points to thinning and flattening of lining epithelium. (b) Acinus at the periphery of the field is lined bytall columnar epithelial cells showing nuclear stratification. Arrow points to polymorphonuclear acute inflammatory cell infiltrate in stroma near the acini. (c)-(d) Prostate of rats treated with RO scale extract in a dose of 150 mg/kg showing. (c) Arrow pointing to reduced acinar distension which are lined by tall columnar cells exhibiting nuclear stratification. (d) Arrow pointing to luminal karyorrhectic debris. (e) Prostate of rats treated with RO scales in a dose of 300 mg/kg showing. Thin arrow points to luminal karyorrhectic debris and thick arrow points to hyperplasia as seen by tall columnar cells lining the acini with nuclear stratification (at 60X).