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Mediators of Inflammation
Volume 2014, Article ID 641039, 7 pages
http://dx.doi.org/10.1155/2014/641039
Clinical Study

Serum Soluble Triggering Receptor Expressed on Myeloid Cells-1 and Procalcitonin Can Reflect Sepsis Severity and Predict Prognosis: A Prospective Cohort Study

1Intensive Care Unit, The Second Hospital, Tianjin Medical University, Tianjin 300211, China
2Cardiology Department, The Second Hospital, Tianjin Medical University, Tianjin 300211, China

Received 20 September 2013; Revised 8 December 2013; Accepted 9 December 2013; Published 4 February 2014

Academic Editor: Vinod K. Mishra

Copyright © 2014 Zhenyu Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. C. Angus, W. T. Linde-Zwirble, J. Lidicker, G. Clermont, J. Carcillo, and M. R. Pinsky, “Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care,” Critical Care Medicine, vol. 29, no. 7, pp. 1303–1310, 2001. View at Google Scholar · View at Scopus
  2. A. Bouchon, J. Dietrich, and M. Colonna, “Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes,” Journal of Immunology, vol. 164, no. 10, pp. 4991–4995, 2000. View at Google Scholar · View at Scopus
  3. S. Gibot, A. Cravoisy, B. Levy, M.-C. Bene, G. Faure, and P.-E. Bollaert, “Soluble triggering receptor expressed on myeloid cells and the diagnosis of pneumonia,” The New England Journal of Medicine, vol. 350, no. 5, pp. 451–458, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Assicot, D. Gendrel, H. Carsin, J. Raymond, J. Guilbaud, and C. Bohuon, “High serum procalcitonin concentrations in patients with sepsis and infection,” The Lancet, vol. 341, no. 8844, pp. 515–518, 1993. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Clerico, F. A. Recchia, C. Passino, and M. Emdin, “Cardiac endocrine function is an essential component of the homeostatic regulation network: physiological and clinical implications,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 290, no. 1, pp. H17–H29, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. S. M. A. Lobo, F. R. M. Lobo, D. P. Bota et al., “C-reactive protein levels correlate with mortality and organ failure in critically III patients,” Chest, vol. 123, no. 6, pp. 2043–2049, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Gibot, M. N. Kolopp-Sarda, M. C. Béné et al., “Plasma level of a triggering receptor expressed on myeloid cells-1: its diagnostic accuracy in patients with suspected sepsis,” Annals of Internal Medicine, vol. 141, no. 1, pp. 9–15, 2004. View at Google Scholar
  8. J. Phua, E. S. C. Koay, D. Zhang, and K. H. Lee, “How well do serum sTREM-1 measurements prognosticate in septic shock?” Anaesthesia and Intensive Care, vol. 36, no. 5, pp. 654–658, 2008. View at Google Scholar · View at Scopus
  9. M. M. Levy, M. P. Fink, J. C. Marshall et al., “2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference,” Critical Care Medicine, vol. 31, no. 4, pp. 1250–1256, 2003. View at Publisher · View at Google Scholar · View at Scopus
  10. L.-X. Su, L. Feng, J. Zhang et al., “Diagnostic value of urine sTREM-1 for sepsis and relevant acute kidney injuries: a prospective study,” Critical Care, vol. 15, no. 5, article R250, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. J. Zhang, D. She, D. Feng, Y. Jia, and L. Xie, “Dynamic changes of serum soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) reflect sepsis severity and can predict prognosis: a prospective study,” BMC Infectious Diseases, vol. 11, article 53, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Jiyong, H. Tiancha, C. Wei, and S. Huahao, “Diagnostic value of the soluble triggering receptor expressed on myeloid cells-1 in bacterial infection: a meta-analysis,” Intensive Care Medicine, vol. 35, no. 4, pp. 587–595, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. C. Bopp, S. Hofer, A. Bouchon, J. B. Zimmermann, E. Martin, and M. A. Weigand, “Soluble TREM-1 is not suitable for distinguishing between systemic inflammatory response syndrome and sepsis survivors and nonsurvivors in the early stage of acute inflammation,” European Journal of Anaesthesiology, vol. 26, no. 6, pp. 504–507, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. A. A. Dahaba and H. Metzler, “Procalcitonin's role in the sepsis cascade. Is procalcitonin a sepsis marker or mediator?” Minerva Anestesiologica, vol. 75, no. 7-8, pp. 447–452, 2009. View at Google Scholar · View at Scopus
  15. A. Nakamura, H. Wada, M. Ikejiri et al., “Efficacy of procalcitonin in the early diagnosis of bacterial infections in a critical care unit,” Shock, vol. 31, no. 6, pp. 586–591, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. G. P. Castelli, C. Pognani, M. Cita, and R. Paladini, “Procalcitonin as a prognostic and diagnostic tool for septic complications after major trauma,” Critical Care Medicine, vol. 37, no. 6, pp. 1845–1849, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. C. Clec'h, F. Ferriere, P. Karoubi et al., “Diagnostic and prognostic value of procalcitonin in patients with septic shock,” Critical Care Medicine, vol. 32, no. 5, pp. 1166–1169, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. C. P. Schneider, Y. Yilmaz, A. Kleespies, K.-W. Jauch, and W. H. Hartl, “Accuracy of procalcitonin for outcome prediction in unselected postoperative critically ill patients,” Shock, vol. 31, no. 6, pp. 568–573, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. T. Szakmany and Z. Molnar, “Procalcitonin levels do not predict mortality following major abdominal surgery,” Canadian Journal of Anesthesia, vol. 50, no. 10, pp. 1082–1083, 2003. View at Google Scholar · View at Scopus
  20. F. Wang, Y. Wu, L. Tang et al., “Brain natriuretic peptide for prediction of mortality in patients with sepsis: a systematic review and meta-analysis,” Critical Care, vol. 16, no. 3, article R74, pp. 1–12, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. A. Kotanidou, P. Karsaliakos, M. Tzanela et al., “Prognostic importance of increased plasma amino-terminal pro-brain natriuretic peptide levels in a large noncardiac, general intensive care unit population,” Shock, vol. 31, no. 4, pp. 342–347, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Póvoa, “C-reactive protein: a valuable marker of sepsis,” Intensive Care Medicine, vol. 28, no. 3, pp. 235–243, 2002. View at Publisher · View at Google Scholar · View at Scopus
  23. H. B. Reith, U. Mittelkötter, R. Wagner, and A. Thiede, “Procalcitonin (PCT) in patients with abdominal sepsis,” Intensive Care Medicine, vol. 26, no. 2, pp. S165–S169, 2000. View at Google Scholar · View at Scopus
  24. A. Luzzani, E. Polati, R. Dorizzi, A. Rungatscher, R. Pavan, and A. Merlini, “Comparison of procalcitonin and C-reactive protein as markers of sepsis,” Critical Care Medicine, vol. 31, no. 6, pp. 1737–1741, 2003. View at Publisher · View at Google Scholar · View at Scopus
  25. M. Suárez-Santamaría, F. Santolaria, A. Pérez-Ramírez et al., “Prognostic value of inflammatory markers (notably cytokines and procalcitonin), nutritional assessment, and organ function in patients with sepsis,” European Cytokine Network, vol. 21, no. 1, pp. 19–26, 2010. View at Publisher · View at Google Scholar
  26. P. Fraunberger, Y. Wang, E. Holler et al., “Prognostic value of interleukin 6, procalcitonin, and C-reactive protein levels in intensive care unit patients during first increase of fever,” Shock, vol. 26, no. 1, pp. 10–12, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. P. Kawczyński and E. Polakowska, “Plasma levels of C-reactive protein, procalcitonin, interleukin-6 and interleukin-10 in preterm neonates evaluated for nosocomial sepsis,” Medical Science Monitor, vol. 10, supplement 2, pp. 58–61, 2004. View at Google Scholar
  28. C. P. Schneider, Y. Yilmaz, A. Kleespies, K.-W. Jauch, and W. H. Hartl, “Accuracy of procalcitonin for outcome prediction in unselected postoperative critically ill patients,” Shock, vol. 31, no. 6, pp. 568–573, 2009. View at Publisher · View at Google Scholar · View at Scopus
  29. S. Kibe, K. Adams, and G. Barlow, “Diagnostic and prognostic biomarkers of sepsis in critical care,” Journal of Antimicrobial Chemotherapy, vol. 66, supplement 2, pp. ii33–ii40, 2011. View at Publisher · View at Google Scholar · View at Scopus