Research Article

Effect of the Toll-Like Receptor 4 Antagonist Eritoran on Retinochoroidal Inflammatory Damage in a Rat Model of Endotoxin-Induced Inflammation

Table 2

Histopathological scores of study groups.

ā€‰Histopathological scoresā€‰LPS + salineLPS + eritoranTotal

12th hourMinimal (%) 7 (70.0) 9 (90.0)16 (80.0)
Mild (%) 3 (30.0) 1 (10.0) 4 (20.0)
Moderate (%) 0 (0.0) 0 (0.0) 0 (0.0)
Severe (%) 0 (0.0) 0 (0.0) 0 (0.0)
Very severe (%) 0 (0.0) 0 (0.0) 0 (0.0)
Total (%)10 (100.0)10 (100.0)20 (100.0)

24th hourMinimal (%) 0 (00.0) 6 (60.0) 6 (30.0)
Mild (%) 9 (90.0) 4 (40.0)13 (65.0)
Moderate (%) 1 (10.0) 0 (0.0) 1 (5.0)
Severe (%) 0 (0.0) 0 (0.0) 0 (0.0)
Very severe (%) 0 (0.0) 0 (0.0) 0 (0.0)
Total (%)10 (100.0)10 (100.0)20 (100.0)

LPS: lipopolysaccharide.