Clinical Study

Selective Vitamin D Receptor Activation as Anti-Inflammatory Target in Chronic Kidney Disease

Table 1

Demographic and baseline serum biochemistries of patients in the study and control groups.

VariableStudy group
( )
Control group
( )
P value

Age (years) NS
Diabetes3 (37.5%)3 (33.3%)NS
Phosphate (mg/dL)4.2 (3.7–4.5)4.4 (3.8–4.8)NS
Calcium (mg/dL)8.9 (8.3–9.7)9.0 (8.5–9.9)NS
Ca × P (mg2/dL2)37 (35–42)39 (34–43)NS
Intact PTH (pg/mL)201 (166–228)136 (127–148)<0.01
hs-CRP (mg/L)4.9 (3.3–7.7)4.9 (3.9–8.0)NS
TNF- (pg/mL)7.8 (5.1–9.0)7.6 (5.5–9.2)NS
Interleukin-6 (pg/mL)6.5 (2–12)6.8 (2.8–11.2)NS
Interleukin-10 (pg/mL)67 (41–125)72 (32–101)NS

Ca × P: calcium-phosphate product; PTH: parathyroid hormone; hs-CRP: high-sensitive C-reactive protein; TNF- : tumor necrosis factor- ; NS: not significant.