LPS-Challenged TNFα Production, Prostaglandin Secretion, and TNFα/TNFRs Expression in the Endometrium of Domestic Cats in Estrus or Diestrus, and in Cats with Pyometra or Receiving Medroxyprogesterone Acetate
Figure 7
TNFR2 protein localization in endometria. Immunohistochemical (IHC) localization of TNFR2 in the endometria of cats collected at (a) estrus phase (E, ) and (b) diestrus phase (D, ) from (c) cats that had been treated with a P4 derivative analog, medroxyprogesterone acetate (MPA, ); or (d) cats presenting the clinical symptoms of pyometra (PYO; ). In females at (a) estrus and (b) diestrus, TNFR2 expression is localized in the glandular and surface epithelium; (c) in MPA females, very strong signals are observed in the endometrial glands, whereas (d) in PYO females, strong signals are present in surface and glandular epithelium and weaker ones in endometrial stroma. Surface epithelium: white arrowheads; glandular epithelium: white arrows; endometrial stroma: black arrows.
