Monocyte Subsets in Schistosomiasis Patients with Periportal Fibrosis

Figure 3

Mean fluorescence intensity (MFI) expression of profibrotic IL-4Rα ((a)–(c)) and TGF-β ((d)–(f)) and proinflammatory IL-6 ((g)–(i)) and TNF-α ((j)–(l)) molecules in classical (CD14⁺⁺CD16⁻), intermediate (CD14⁺⁺CD16⁺), and nonclassical (CD14⁺CD16⁺⁺) monocytes, of patients with different degrees of periportal fibrosis secondary to schistosomiasis. Cultures without stimulus (white bar) and cultures stimulated with 10 μg/mL SEA (gray bar). Without fibrosis (WF), incipient fibrosis (IF), and moderate to severe fibrosis (MSF). ^∗𝑃<0.05 and ^∗∗𝑃<0.005 (Kruskal-Wallis).

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