Research Article

Effect of Low-Dose, Long-Term Roxithromycin on Airway Inflammation and Remodeling of Stable Noncystic Fibrosis Bronchiectasis

Table 2

Effect of roxithromycin on the inflammatory cell (106/mL) in induced sputum inflammatory markers in sputum.

ParametersGroup Baseline6 months value
6 months versus baseline
value
versus control at baseline
value
versus control at 6 months

Total cellsControl0.069
Roxithromycin0.0010.211<0.001

NeutrophilsControl0.055
Roxithromycin<0.0010.129<0.001

MacrophagesControl0.079
Roxithromycin0.8780.7620.170

LymphocytesControl0.915
Roxithromycin0.2970.6060.142

( = 0.001 and ) compared with 6 months of controls.