Research Article
Effect of Low-Dose, Long-Term Roxithromycin on Airway Inflammation and Remodeling of Stable Noncystic Fibrosis Bronchiectasis
Table 2
Effect of roxithromycin on the inflammatory cell (106/mL) in induced sputum inflammatory markers in sputum.
| Parameters | Group | Baseline | 6 months | value 6 months versus baseline | value versus control at baseline | value versus control at 6 months |
| Total cells | Control | | | 0.069 | | | Roxithromycin | | | 0.001 | 0.211 | <0.001 |
| Neutrophils | Control | | | 0.055 | | | Roxithromycin | | | <0.001 | 0.129 | <0.001 |
| Macrophages | Control | | | 0.079 | | | Roxithromycin | | | 0.878 | 0.762 | 0.170 |
| Lymphocytes | Control | | | 0.915 | | | Roxithromycin | | | 0.297 | 0.606 | 0.142 |
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( = 0.001 and ) compared with 6 months of controls.
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