Circumsporozoite Protein-Specific K^d-Restricted CD8+ T Cells Mediate Protective Antimalaria Immunity in Sporozoite-Immunized MHC-I-K^d Transgenic Mice

Figure 1

Phenotype of MHC-I- 𝐾^𝑑-Tg mice. Histograms show H-2K^d expression levels on hepatocytes, macrophages, dendritic cells, and lymphocytes of C57BL/6 (B6), MHC-I-K^d-Tg, and BALB/c. Hepatocytes were isolated from mouse liver and then gated based on high FSC/SSC parameters. Macrophages were gated on CD11b+/F4/80+ and CD11c+/MHC II+ were used to define dendritic cells. Lymphocytes were identified by CD11c−/F4/80−.