Polymorphisms in the Tumor Necrosis Factor Receptor Genes Affect the Expression Levels of Membrane-Bound Type I and Type II Receptors

Figure 5

(a) Percentage of CD3⁺ cells expressing TNFRII in individuals presenting with different genotypes combinations of SNPs TNFRI −609G/T (rs4149569) and TNFRII −3609C/T (rs590368). Kruskal-Wallis 𝐻 test, 𝑃=0.048, Mann-Whitney 𝑈 test: GT+CC versus GG+CT, 𝑃=0.01. (b) Percentage of CD14⁺ cells expressing TNFRII in individuals with different genotypes combinations of SNPs TNFRI −609G/T (rs4149569) and TNFRII −3609C/T (rs590368). Mann-Whitney 𝑈 test: GT+CC versus GT+CT, 𝑃=0.046, GT+CC versus GG+CT, 𝑃=0.04.

(a)

(b)