Research Article
Polymorphisms in the Tumor Necrosis Factor Receptor Genes Affect the Expression Levels of Membrane-Bound Type I and Type II Receptors
Table 4
Frequency of genotypes combinations of TNFRI and TNFRII in patients with rheumatoid arthritis and healthy individuals.
| Genotypes
TNFRI
−609 | Genotypes
TNFRII
−3609 | Frequency of combination in RA,
%, (n) | Frequency of combination in control
%, (n) |
| | GT | CT |
25.8 (110) | 24.2 (36) | | GT | CC | 10.6 (45)* | 22.1 (33) | | GG | CT | 22.5 (96) | 16.8 (25) | | GG | CC | 12.9 (55) | 9.4 (14) | | TT | CT | 7.0 (30) | 9.4 (14) | | GT | TT | 7.3 (31) | 6 (9) | | GG | TT | 6.1 (26) | 4.7 (7) | | TT | CC | 4.9 (21) | 4 (6) | | TT | TT | 2.8 (12) | 3.4 (5) |
|
|
Statistical significant difference, .
|
