Korean Red Ginseng Saponin Fraction Rich in Ginsenoside-Rb1, Rc and Rb2 Attenuates the Severity of Mouse Collagen-Induced Arthritis

<table>RGSF-A modulates CIA anti-CII IgG and rheumatoid factor (RF) serum antibody levels in mice. (a) Total anti-CII IgG antibody level was measured by enzyme-linked immunosorbent assay (ELISA) in mice treated with RGSF-A, MTX, or vehicle. The serum levels of RF IgG (b) and RF IgM (c) were determined by ELISA. <svg height="13.95" id="M13" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 66.324997 13.95" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> as compared with vehicle treatment; <svg height="11.225" id="M16" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> for each group.</table>

Mediators of Inflammation

fig5

Figure 5

Figure 5: Korean Red Ginseng Saponin Fraction Rich in Ginsenoside-Rb1, Rc and Rb2 Attenuates the Severity of Mouse Collagen-Induced Arthritis 