Impact of STAT/SOCS mRNA Expression Levels after Major Injury
Figure 3
Posttraumatic SOCS 1 mRNA expression profiles after major trauma in all patients (a), depending on injury severity (NISS, (b)) and depending on outcome (survival > 90 days, (c)), * SNK-test, #U test. SOCS 1 mRNA expression levels significantly decreased after 6 h–72 h compared to SOCS 1 levels measured on admission (A). SOCS 1 mRNA levels of both subgroups (groups 1 and 2) decreased significantly in the early posttraumatic period (6 h–72) compared to SOCS 1 levels on admission (A). There was no significant difference between the subgroups (group 1/group 2). SOCS 1 mRNA levels significantly decreased in survivors (group A) in the posttraumatic observation period (6 h–72 h) in comparison to SOCS 1 mRNA expression detected on admission (A).
