The Role of IL-17 Promotes Spinal Cord Neuroinflammation via Activation of the Transcription Factor STAT3 after Spinal Cord Injury in the Rat
Figure 1
The severity of SCI was evaluated using hematoxylin-eosin staining (original magnification ×400). The spinal cord tissues were normal in the sham-operated group (a). The spinal cord demonstrated obvious sign of compression following SCI and the organization structure was destroyed as observed in (b). Next, the degree of inflammation gradually increased. A few scattered small foci of hemorrhage from small veins and capillaries and nerve cells are swollen and necrosis was observed at 24 h (c). The severity of the nerve cell necrosis and interstitial inflammatory cell infiltration were markedly increased at 48 h (d). Extensive hemorrhage and nerve cell necrosis was observed in at 72 h (e). Bar equals 50 μm.
