The Role of IL-17 Promotes Spinal Cord Neuroinflammation via Activation of the Transcription Factor STAT3 after Spinal Cord Injury in the Rat
Figure 5
(a) and (b): IL-17 and IL-23p19 mRNA transcription in spleen tissue. Representative images showed semiquantitative RT-PCR for IL-17 and IL-23p19 transcription sham. The sham-operated group; 1 h. The 1 h group of SCI; 24 h. The 24 h group of SCI; 48 h. The 48 h group of SCI; 72 h. The 72 h group of SCI. (c) and (d): densitometric quantification of IL-17 and IL-23p19mRNA expression in spleen tissues. Densitometric quantification of PCR bands showed that, among the IL-17 and IL-23p19, the sham-operated group, 1 h group of SCI, 24 h group of SCI, 48 h group of SCI, and 72 h group of SCI, the mRNA expression was significantly difference between each groups and peaked at 24 h. The data are presented as the mean ± the SE. versus sham, # versus 1 h, △ versus 24 h, and ● versus 48 h.
