Research Article
Serum Amyloid A as a Marker of Persistent Inflammation and an Indicator of Cardiovascular and Renal Involvement in Patients with Rheumatoid Arthritis
Table 2
Clinical and laboratory variables in 140 RA patients.
| | Variable | Results |
| | Clinical variables | | | Systolic BP (mmHg) | 126.6 (14.2) (range 90–160) | | Diastolic BP (mmHg) | 79.5 (9.3) (range 50–100) | | BMI (kg/m2) | 24.6 (3.8) (range 16–38.3) | | SCORE (%) | 1.7 (2.6) (range 0–12) | | cIMT (mm) | 0.79 (0.15) (range 0.43–1.2) | | Plaques present | 40 (28.6%) | | QTc (ms) | 335.5 (57.8) (range 186–487) | | Laboratory variables | | | CRP (mg/L) | 19.5 (22.5) (range 0.1–116) | | ESR (mm/h) | 35.9 (24.3) (range 5–102) | | Hemoglobin (g/dL) | 12.5 (1.3) (range 9.2–16.4) | | Total protein (g/dL) | 7.1 (0.6) (range 4.2–8.4) | | Albumin (g/dL) | 4.2 (0.4) (range 2.3–5.0) | | Fibrinogen (g/L) | 4.8 (1.3) (range 2.0–9.0) | | Total cholesterol (mg/dL) | 200.1 (45.2) (range 98–365) | | HDL-C (mg/dL) | 59.9 (15.8) (range 32–115) | | LDL-C (mg/dL) | 117.4 (34.9) (range 38–245) | | Triglycerides (mg/dL) | 117.3 (55.5) (range 24–300) | | Serum creatinine (mg/dL) | 0.71 (0.23) (range 0.4–2.3) | | MDRD-eGFR (mL/min/1.73 m2) | 106.0 (26.7) (range 22.9–156) | | Cystatin-C (mg/L) | 0.77 (0.22) (range 0.42–1.66) | | Serum amyloid A (mg/L) | 327.0 (263.4) (range 0–733.2) |
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Values are mean (SD) or numbers (%).
BP: blood pressure; BMI: body mass index; SCORE: systemic coronary risk evaluation; cIMT: carotid intima-media thickness; CRP: C-reactive protein; QTc: corrected QT interval; ESR: erythrocyte sedimentation rate; HDL-C: high-density lipoprotein cholesterol, LDL-C: low-density lipoprotein cholesterol; MDRD-eGFR: estimated glomerular filtration by modification of diet in renal disease.
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