Maternal Plasma and Amniotic Fluid Chemokines Screening in Fetal Down Syndrome
Table 2
Concentrations of chemokines in maternal plasma.
Group I: Down syndrome pregnancies
Group II: pregnancies without Down syndrome
value
Chemokines concentration (pg/mL) Mean ± SEM
Group I- Group II
6Ckine
14976.6 ± 2072.06
20710.7 ± 4887.08
0.9710
Axl
1172.4 ± 83
1480.5 ± 249.07
0.9131
BTC
10605.3 ± 977.53
13437 ± 2241.25
0.9131
CCL28
7630.3 ± 220.64
9056.4 ± 1261.94
0.9710
CTACK/CCL27
3830.2 ± 305.44
4685.3 ± 714.14
0.7990
CXCL16
6781.2 ± 452.89
7501.4 ± 731.94
0.5182
ENA-78/CXCL5
3257.3 ± 193.33
5164.2 ± 1146.31
0.9131
Eotaxin-3
2079.1 ± 250.3
2895.2 ± 357.21
0.2245
GCP-2
499.5 ± 46.54
695.8 ± 106.2
0.2221
GRO α, β, γ/CXCL1, CXCL2, CXCL3
498.3 ± 41.08
483.7 ± 39.24
0.8186
HCC-1/CCL14
1438.4 ± 160.58
1610.5 ± 114.67
0.3956
HCC-4/CCL16
1401.8 ± 172.58
1783.4 ± 93.38
0.0462
IL-9
82744.2 ± 6237.34
112569.1 ± 23155.3
0.7573
IL-17F
1581.4 ± 161.2
4763 ± 1302.6
0.1490
IL-18 BPa
6866.4 ± 850.07
8645.5 ± 1553.04
0.9710
IL-28A
282.3 ± 29.8
728.7 ± 159.33
0.0319
IL-29
17435 ± 1282.24
20785.5 ± 3212.95
0.9710
IL-31
418.7 ± 47.19
1971.5 ± 495.91
0.0309
IP-10/CXCL10
694.7 ± 38.72
706.6 ± 82.24
0.3601
I-TAC/CXCL11
119.5 ± 16.09
261.1 ± 67.8
0.2245
LIF
1588.3 ± 117.81
2350.8 ± 432.73
0.5846
LIGHT/TNFSF14
159.6 ± 6.18
281.4 ± 56.17
0.3601
Lymphotactin/XCL1
2345.9 ± 135.17
3093.7 ± 467.96
0.7433
MCP-2/CCL8
24.4 ± 1.7
38.7 ± 5.08
0.0125
MCP-3/CCL7
112.5 ± 11.63
172.2 ± 34.83
0.6888
MCP-4/CCL13
155.4 ± 14.35
232.26 ± 36.49
0.1647
MDC/CCL22
3408 ± 330.74
3036.5 ± 283.09
0.4342
MIF
920.3 ± 278.35
945.5 ± 127.95
0.9254
MIP-3a (CCL20)
12.1 ± 1.08
34.8 ± 8.69
0.0811
MIP-3b/CCL19
816.9 ± 79.04
1910.2 ± 447.75
0.0938
MPIF1/CCL23
2967.3 ± 372.87
2583 ± 306.44
0.2872
MSPa
3475.8 ± 702.62
4182.9 ± 626.75
0.4965
NAP-2/CXCL7
195.3 ± 13.96
154.3 ± 10.85
0.0370
OPN
8999.1 ± 3494.15
10607.3 ± 2222.93
0.6359
PARC/CCL18
2429.1 ± 216.55
2552.5 ± 322.64
0.6359
PF4
15460.4 ± 1005.84
19633.4 ± 2102.81
0.1929
SDF-1/CXCL12
275.1 ± 31.54
462.6 ± 104.53
0.5846
TARC/CCL17
29.9 ± 4.92
85.2 ± 32.58
0.9671
TECK/CCL25
6428.8 ± 585.25
9590.1 ± 2064.78
0.8557
TSLP
364.2 ± 25.3
1559.4 ± 438.2
0.0793
Statistically significant value of less than 0.05 for Student’s -test. Statistically significant value of less than 0.05 for Mann-Whitney-Wilcoxon test.
