Maternal Plasma and Amniotic Fluid Chemokines Screening in Fetal Down Syndrome

Table 4

Diagnostic values of chemokines in plasma.

	Threshold value (pg/mL)	Sensitivity	95% CI for sensitivity	Specificity	95% CI for specificity	AUC	95% CI for AUC	Std. error	value
HCC-4	<1574.65	0.8571	0.4868–0.9743	0.7142	0.4535–0.8827	0.73	0.51–1	0.13	0.0412
IL-31	<443.6	0.7142	0.3589–0.9177	0.8571	0.6005–0.9599	0.79	0.63–1	0.1	0.0018
IL-28A	<397.33	1	0.6456–1	0.7142	0.4535–0.8827	0.79	0.63–1	0.1	0.0017
MCP-2	<30.28	1	0.6456–1	0.7142	0.4535–0.8827	0.84	0.69–1	0.09	0.0001
CXCL7	>171.56	0.8571	0.4868–0.9743	0.7142	0.4535–0.8827	0.79	0.63–1	0.1	0.0015