IVS1 −397T>C Estrogen Receptor α Polymorphism Is Associated with Low-Grade Systemic Inflammatory Response in Type 1 Diabetic Girls

Table 2

Serum level of 17β-estradiol in DM1 and healthy young girls differing in the IVS1 −397T>C estrogen receptor α polymorphism.

	CC	CT	TT	𝑃	𝑃^∗	𝑃^∗∗	𝑃^∗∗∗
Control group	217 ± 59	234.6 ± 152.9	220.1 ± 74.3	0.86	0.8	0.69	0.89
DM1	281.1 ± 262.6	248.3 ± 130.3	141.4 ± 75.5	0.028	0.28	0.06	0.04

Differences were calculated by the Kruskal-Wallis ANOVA test. Data are presented as mean ± SD.
The values are presented as pmol/L.
𝑃: the comparison between three analyzed genotypes CC, CT and TT.
𝑃^∗: post hoc comparison between patients bearing CC and CT genotypes.
𝑃^∗∗: post hoc comparison between patients bearing CT and TT genotypes.
𝑃^∗∗∗: post hoc comparison between patients bearing CC and TT genotypes.