IVS1 −397T>C Estrogen Receptor α Polymorphism Is Associated with Low-Grade Systemic Inflammatory Response in Type 1 Diabetic Girls

Table 6

The results of the correlation analysis between serum level of 17β-estradiol, Th17 subset, and the concentrations of analyzed cytokines in DM1 patients.

	IL-6	TNF-α	VEGF	IL-10
Serum level of 17β-estradiol	𝑅=[−0.2]	𝐑=[−𝟎.𝟕𝟏]	𝐑=[−𝟎.𝟖𝟔]	𝑅=0.2
	𝑃>0.05	𝑃<0.05	𝑃<0.05	𝑃>0.05
The percentage of CD4^+IL17A^+ T cells (%)*	𝐑=𝟎.𝟓𝟓	𝑅=0.45	𝐑=𝟎.𝟒𝟔	𝐑=[−𝟎.𝟔𝟒]
	𝑃<0.05	𝑃>0.05	𝑃<0.05	𝑃<0.05

The Spearman test was used to calculate the strength of correlation.
*The percentage of cells among peripheral blood lymphocytes.