Inhibition of Ocular Aldose Reductase by a New Benzofuroxane Derivative Ameliorates Rat Endotoxic Uveitis

Figure 4

Western blotting analysis for NF-κB. Injection of BF-5m (0.01; 0.05; 0.1 μM/rat) into the vitreous 24 h after LPS-treatment of the rats reduced the expression of activated NF-κB 105 (a), p50 (b), and p65 (c). Results are expressed as densitometric units and represented the mean ± SEM of observations for each group. versus vehicle saline group and versus LPS-treated rats.

(a)

(b)

(c)