The Effect of Serine Protease Inhibitors on Airway Inflammation in a Chronic Allergen-Induced Asthma Mouse Model
Effects of protease inhibitors on IL-6 and IL-17A gene expression and NF-κB activity in lung tissue. (a) Relative IL-6 and IL-17A mRNA expression in lung tissue. Results are expressed as means ± SDs for 6 mice/group. versus naïve group; between Der p-treated groups and (b) EMSA showed that all three serine protein inhibitors decreased NF-κB activation in lung tissue after Der p stimulation. The arrow indicates the specific DNA-probe complex.